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Mouse Anti-CRTAC1 Recombinant Antibody (CBXC-1313) (CBMAB-C5784-CQ)

This product is a mouse antibody that recognizes CRTAC1. The antibody CBXC-1313 can be used for immunoassay techniques such as: ICC.
See all CRTAC1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-1313
Antibody Isotype
IgG2b
Application
ICC

Basic Information

Immunogen
NS0-derived recombinant human CRTAC1, Ser28-Cys661, Accession # Q9NQ79
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
Lyophilized from PBS
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cartilage Acidic Protein 1
Introduction
CRTAC1 (Cartilage Acidic Protein 1) is a Protein Coding gene. Diseases associated with CRTAC1 include Bone Fracture. Gene Ontology (GO) annotations related to this gene include calcium ion binding.
Entrez Gene ID
55118
UniProt ID
Q9NQ79
Alternative Names
Cartilage Acidic Protein 1; ASPIC1; CEP-68; ASPIC; Chondrocyte Expressed Protein 68 KDa CEP-68; Acidic Secreted Protein In Cartilage; 8 KDa Chondrocyte-Expressed Protein; Cep68;
Cellular Location
Extracellular matrix
PTM
O-glycosylated.

Yang, J., Fan, L., Liao, X., Cui, G., & Hu, H. (2021). CRTAC1 (Cartilage acidic protein 1) inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) process in bladder cancer by downregulating Yin Yang 1 (YY1) to inactivate the TGF-β pathway. Bioengineered, 12(2), 9377-9389.

Félix, R. C., Anjos, L., Costa, R. A., Letsiou, S., & Power, D. M. (2021). Cartilage Acidic Protein a Novel Therapeutic Factor to Improve Skin Damage Repair?. Marine Drugs, 19(10), 541.

Styrkarsdottir, U., Lund, S. H., Saevarsdottir, S., Magnusson, M. I., Gunnarsdottir, K., Norddahl, G. L., ... & Stefansson, K. (2021). The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large‐Scale Proteomics Scan in Iceland. Arthritis & Rheumatology, 73(11), 2025-2034.

Kuwashiro, T., Tanabe, K., Hayashi, C., Mizoguchi, T., Mori, K., Jinnouchi, J., ... & Okada, Y. (2021). Oxidized Albumin and Cartilage Acidic Protein-1 as Blood Biomarkers to Predict Ischemic Stroke Outcomes. Frontiers in neurology, 2233.

Letsiou, S., Manchado, M., Zografaki, M., Marka, S., Anjos, L., Skliros, D., ... & Power, D. M. (2021). Deciphering the role of cartilage protein 1 in human dermal fibroblasts: a transcriptomic approach. Functional & Integrative Genomics, 21(3), 503-511.

Sun, Y., Rong, X., Li, D., Lu, Y., & Ji, Y. (2020). NF-κB/cartilage acidic protein 1 promotes ultraviolet B irradiation-induced apoptosis of human lens epithelial cells. DNA and Cell Biology, 39(4), 513-521.

Letsiou, S., Félix, R. C., Cardoso, J. C., Anjos, L., Mestre, A. L., Gomes, H. L., & Power, D. M. (2020). Cartilage acidic protein 1 promotes increased cell viability, cell proliferation and energy metabolism in primary human dermal fibroblasts. Biochimie, 171, 72-78.

Anjos, L., Morgado, I., Guerreiro, M., Cardoso, J. C., Melo, E. P., & Power, D. M. (2017). Cartilage acidic protein 1, a new member of the beta‐propeller protein family with amyloid propensity. Proteins: Structure, Function, and Bioinformatics, 85(2), 242-255.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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