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Mouse Anti-CRYBA4 (AA 96-195) Recombinant Antibody (CBFYC-2251) (CBMAB-C2322-FY)

This product is mouse antibody that recognizes CRYBA4. The antibody CBFYC-2251 can be used for immunoassay techniques such as: ELISA, WB.
See all CRYBA4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-2251
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Immunogen
CRYBA4 (NP_001877, 96 a.a.-195 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: PAACANHRDS RLTIFEQENF LGKKGELSDD YPSLQAMGWE GNEVGSFHVH SGAWVCSQFP GYRGFQYVLE CDHHSGDYKH FREWGSHAPT FQVQSIRRIQ
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 96-195

Target

Full Name
crystallin, beta A4
Introduction
CRYBA4 (Crystallin Beta A4) is a Protein Coding gene. Diseases associated with CRYBA4 include Cataract 23, Multiple Types and Cataract Microcornea Syndrome. Gene Ontology (GO) annotations related to this gene include structural constituent of eye lens. An important paralog of this gene is CRYBA1.
Entrez Gene ID
UniProt ID
Alternative Names
Crystallin Beta A4; Beta-A4 Crystallin; Beta Crystallin A4 Chain Transcript PS; Crystallin, Beta Polypeptide A4; Beta Crystallin Alpha 4 Chain; Eye Lens Structural Protein
Function
Crystallins are the dominant structural components of the vertebrate eye lens.
Biological Process
Camera-type eye development Source: UniProtKB
Lens development in camera-type eye Source: GO_Central
Visual perception Source: UniProtKB
Involvement in disease
Cataract 23, multiple types (CTRCT23):
An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. CTRCT23 is a zonular cataract. Zonular or lamellar cataracts are opacities, broad or narrow, usually consisting of powdery white dots affecting only certain layers or zones between the cortex and nucleus of an otherwise clear lens. The opacity may be so dense as to render the entire central region of the lens completely opaque, or so translucent that vision is hardly if at all impeded. Zonular cataracts generally do not involve the embryonic nucleus, though sometimes they involve the fetal nucleus. Usually sharply separated from a clear cortex outside them, they may have projections from their outer edges known as riders or spokes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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