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Mouse Anti-CRYZ Recombinant Antibody (2A9DD1) (CBMAB-1451-CN)

This product is a mouse antibody that recognizes CRYZ of human. The antibody 2A9DD1 can be used for immunoassay techniques such as: IF, IP, ELISA.
See all CRYZ antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2A9DD1
Antibody Isotype
IgG2a, Κ
Application
IF, IP, ELISA

Basic Information

Immunogen
Tissue, cells or virus corresponding to CRYZ. Human liver mitochondria.
Specificity
Human
Antibody Isotype
IgG2a, Κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HBS
Preservative
0.02% Sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C. Do not freeze.

Target

Full Name
Crystallin Zeta
Introduction
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. Unlike other mammalian species, in humans, lens expression is low. It binds NADP and acts through a one-electron transfer process.
Entrez Gene ID
1429
UniProt ID
Q08257
Alternative Names
quinone oxidoreductase; NADPH:quinone reductase; crystallin, zeta (quinone reductase); EC 1.6.5.5
Function
Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
Biological Process
Protein homotetramerization Source: UniProtKB
Visual perception Source: ProtInc
Xenobiotic catabolic process Source: UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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