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Mouse Anti-CTXB Recombinant Antibody (232-238-10) (CBMAB-0102-CN)

This product is a mouse antibody that recognizes CTXB of Dictyostelium discoideum. The antibody 232-238-10 can be used for immunoassay techniques such as: IHC, WB.
See all CTXB antibodies

Summary

Host Animal
Mouse
Specificity
D. discoideum, Dictyostelium
Clone
232-238-10
Antibody Isotype
IgG1
Application
IHC, WB

Basic Information

Immunogen
N-terminally His-tagged cortexillin II
Specificity
D. discoideum, Dictyostelium
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cortexillin II
Introduction
This gene is a member of the alpha-actinin/spectrin superfamily, dimerizes with cortexillin I. The protein is involved in cytokinesis and development and associates with the actin cytoskeleton.
Entrez Gene ID
8620736
UniProt ID
Q550R2
Alternative Names
FPS1; ctxII
Function
Actin-bundling protein. When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks. Plays a major role in cytokinesis. Negatively regulates cortical localization of rapgap1 (By similarity).
Biological Process
Aggregation involved in sorocarp development Source: dictyBase
Bleb assembly Source: dictyBase
Cell morphogenesis Source: dictyBase
Chemotaxis to cAMP Source: dictyBase
Cortical actin cytoskeleton organization Source: dictyBase
Establishment of protein localization Source: dictyBase
Mitotic cytokinesis Source: dictyBase
Positive regulation of gene expression Source: dictyBase
Positive regulation of protein phosphorylation Source: dictyBase
Regulation of GTPase activity Source: dictyBase
Regulation of myosin II filament assembly Source: dictyBase
Sorocarp development Source: dictyBase
Cellular Location
Cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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