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Mouse Anti-DBP Recombinant Antibody (3A6) (CBMAB-D0312-YC)

Provided herein is a Mouse monoclonal antibody, which binds to D-Box Binding PAR BZIP Transcription Factor (DBP). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all DBP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3A6
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
DBP (NP_001343, 226 a.a. ~ 326 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
D site of albumin promoter (albumin D-box) binding protein
Introduction
DBP is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes.
Entrez Gene ID
1628
UniProt ID
Q10586
Alternative Names
D-Box Binding PAR BZIP Transcription Factor; D Site Of Albumin Promoter (Albumin D-Box) Binding Protein; Tax-Responsive Enhancer Element-Binding Protein 302; Albumin D-Element-Binding Protein; Albumin D Box-Binding Protein; TaxREB302; D Site-Binding Protein; DABP;
Function
This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.
Biological Process
Circadian rhythm Source: InterPro
Liver development Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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