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Mouse Anti-DCLK2 Recombinant Antibody (2A5) (CBMAB-A2103-LY)

The product is antibody recognizes DCAMKL2. The antibody 2A5 immunoassay techniques such as: WB, ELISA.
See all DCLK2 antibodies
Published Data
Fig.1 DCK2 binds to MTs.
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Fig.2 DCK2 expression protects MTs from cold-induced de- polymerization.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
2A5
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
DCAMKL2 (AAH32726, 348 a.a. ~ 438 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Doublecortin Like Kinase 2
Entrez Gene ID
166614
UniProt ID
Q8N568
Alternative Names
DCAMKL2; DCDC3; DCDC3B; DCK2; DKFZp761I032; MGC45428
Function
Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).
Biological Process
Intracellular signal transduction Source: InterPro
Microtubule cytoskeleton organization Source: GO_Central
Cellular Location
Cytoskeleton. Colocalizes with microtubules.
PTM
Autophosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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