Rabbit Anti-DCLK3 Recombinant Antibody (EG931) (CBMAB-EN1103-LY)

The product is antibody recognizes DCLK3. The antibody EG931 immunoassay techniques such as: IHC: 1:50~1:100 ELISA: 1:1000.
See all DCLK3 antibodies

Datasheet

Summary

Host Animal

Rabbit

Specificity

Human

Clone

EG931

Antibody Isotype

IgG

Application

IHC: 1:50~1:100 ELISA: 1:1000

Basic Information

Immunogen

The antibody was produced against synthesized peptide derived from internal of human DCLK3.

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Doublecortin Like Kinase 3

Introduction

DCLK3 (Doublecortin Like Kinase 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is DCLK1.

Entrez Gene ID

85443

UniProt ID

Q9C098

Alternative Names

Doublecortin Like Kinase 3; Doublecortin Domain-Containing Protein 3C; Doublecortin-Like And CAM Kinase-Like 3; Doublecortin And CaM Kinase-Like 3; Doublecortin-Like Kinase 3; EC 2.7.11.1; DCAMKL3; DCDC3C;

Biological Process

Peptidyl-serine phosphorylation Source: GO_Central

Cellular Location

Cytoplasm; Nucleus

References

Zhao, Y., Zhou, H., Shen, J., Yang, S., Deng, K., Li, Q., & Cui, W. (2021). MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3. Frontiers in Oncology, 3363.

Galvan, L., Francelle, L., Gaillard, M. C., de Longprez, L., Carrillo-de Sauvage, M. A., Liot, G., ... & Brouillet, E. (2018). The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin. Brain, 141(5), 1434-1454.

De Longprez, L. (2018). Etude du rôle de la protéine kinase DCLK3 dans les mécanismes de neurodégénérescence dans la maladie de Huntington (Doctoral dissertation, Université Paris Saclay (COmUE)).

Liu, N. Q., Ter Huurne, M., Nguyen, L. N., Peng, T., Wang, S. Y., Studd, J. B., ... & Stunnenberg, H. G. (2017). The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression. Nature communications, 8(1), 1-10.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-DCLK3 Recombinant Antibody (2B1)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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