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Mouse Anti-DEFB104A Recombinant Antibody (4C4) (CBMAB-D0686-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Defensin Beta 104A (DEFB104A). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all DEFB104A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4C4
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to a.a.24-64 from human DEFB4 (NP_004933) with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Defensin Beta 104A
Introduction
Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. DEFB104A represents the more centromeric copy. Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions.
Entrez Gene ID
140596
UniProt ID
Q8WTQ1
Alternative Names
Defensin Beta 104A; Defensin, Beta 104; DEFB104; DEFB-4; DEFB4; HBD-4; BD-4;
Function
Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
Biological Process
Cellular response to phorbol 13-acetate 12-myristate Source: UniProtKB
Defense response to Gram-negative bacterium Source: UniProtKB
Defense response to Gram-positive bacterium Source: UniProtKB
Innate immune response Source: UniProtKB
Monocyte chemotaxis Source: UniProtKB
Positive chemotaxis Source: UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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