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Rabbit Anti-DHRS4 Recombinant Antibody (EG961) (CBMAB-EN1140-LY)

The product is antibody recognizes DHRS4. The antibody EG961 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000.
See all DHRS4 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG961
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human DHRS4.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Dehydrogenase/Reductase 4
Introduction
DHRS4 (Dehydrogenase/Reductase 4) is a Protein Coding gene. Among its related pathways are the visual cycle I (vertebrates) and Peroxisome. Gene Ontology (GO) annotations related to this gene include receptor binding and oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. An important paralog of this gene is DHRS4L2.
Entrez Gene ID
UniProt ID
Alternative Names
Dehydrogenase/Reductase 4; NADPH-Dependent Carbonyl Reductase/NADP-Retinol Dehydrogenase; Short Chain Dehydrogenase/Reductase Family 25C Member 2; Short-Chain Dehydrogenase/Reductase Family Member 4; NADPH-Dependent Retinol Dehydrogenase/Reductase; Peroxisomal Short-Chain Alcohol Dehydrogenase; EC 1.1.1.184; SCAD-SRL; SDR25C2; NRDR; PHCR; PSCD;
Function
Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).
Biological Process
Alcohol metabolic process Source: UniProtKB
Cellular ketone metabolic process Source: UniProtKB
Positive regulation of reactive oxygen species metabolic process Source: UniProtKB
Protein localization Source: Reactome
Steroid metabolic process Source: UniProtKB
Cellular Location
Peroxisome. Isoform 1 is peroxisomal, while isoform 4 is not.
Isoform 7: Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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