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Rabbit Anti-DRP2 (Phosphorylated T514) Polyclonal Antibody (PTM-CBPAB-0655YC) (PTM-CBPAB-0655YC)

Provided herein is a Rabbit polyclonal antibody against Dystrophin Related Protein 2. The antibody can be used for immunoassay techniques, such as ELISA, IF, IHC, WB.
See all DRP2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application
ELISA, IF, IHC, WB

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Dystrophin Related Protein 2
Introduction
Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord.
Entrez Gene ID
Human1821
Mouse13497
Rat66027
UniProt ID
HumanQ13474
MouseQ05AA6
RatQ9EPA0
Alternative Names
Dystrophin Related Protein 2; DRP-2; Dystrophin-Related Protein 2;
Research Area
Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane. Possibly involved in membrane-cytoskeleton interactions of the central nervous system.
Biological Process
Central nervous system development Source: ProtInc
Synapse organization Source: Ensembl
Synaptic signaling Source: GO_Central
Cellular Location
Cell membrane; Postsynaptic density; Dendrite; Perikaryon. Detected in Schwann cells at periaxonal myelin membranes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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