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Mouse Anti-Dsx Recombinant Antibody (2E11.C112) (CBMAB-D1829-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Doublesex (Dsx). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all Dsx antibodies

Summary

Host Animal
Mouse
Specificity
Drosophila
Clone
2E11.C112
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Specificity
Drosophila
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Dsx
Introduction
Dsx controls somatic sexual differentiation. Dsx binds directly and specifically to the FBE (fat body enhancer) of the yolk protein 1 and 2 genes (Yp1 and Yp2). This enhancer is sufficient to direct the female-specific transcription characteristic of the Yp genes in adult fat bodies. Dsx is involved in regulation of male-specific expression of takeout in brain-associated fat body.
Entrez Gene ID
40940
UniProt ID
P23023
Alternative Names
CG11094; Dmdsx; Dmel\CG11094; Dsx; DSX; dsxF; dsxM; Hr; ix-62c
Research Area
Controls somatic sexual differentiation. Binds directly and specifically to the FBE (fat body enhancer) of the yolk protein 1 and 2 genes (Yp1 and Yp2). This enhancer is sufficient to direct the female-specific transcription characteristic of the Yp genes in adult fat bodies. Involved in regulation of male-specific expression of takeout in brain-associated fat body.
Biological Process
Axon midline choice point recognition Source: FlyBase
Courtship behavior Source: FlyBase
Female analia development Source: FlyBase
Female sex differentiation Source: FlyBase
Female somatic sex determination Source: FlyBase
Genital disc development Source: FlyBase
Imaginal disc-derived female genitalia development Source: FlyBase
Imaginal disc-derived male genitalia development Source: FlyBase
Male analia development Source: FlyBase
Male courtship behavior Source: FlyBase
Male courtship behavior, veined wing generated song production Source: FlyBase
Male sex differentiation Source: FlyBase
Negative regulation of developmental pigmentation Source: FlyBase
Negative regulation of transcription, DNA-templated Source: FlyBase
Positive regulation of transcription, DNA-templated Source: FlyBase
Positive regulation of transcription by RNA polymerase II Source: FlyBase
Regulation of transcription by RNA polymerase II Source: FlyBase
Sex comb development Source: FlyBase
Sex determination Source: FlyBase
Sex differentiation Source: GO_Central
Sex-specific pigmentation Source: FlyBase
Somatic sex determination Source: FlyBase
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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