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Rabbit Anti-EIF2AK3 (Phospho-Thr981) Recombinant Antibody (EG1060) (CBMAB-EN1251-LY)

The product is antibody recognizes EIF2AK3 (Phospho-Thr981). The antibody EG1060 immunoassay techniques such as: IHC: 1:50~1:100 ELISA: 1:40000.
See all EIF2AK3 (Phospho-Thr981) antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1060
Antibody Isotype
IgG
Application
IHC: 1:50~1:100 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized phosphopeptide derived from human PEK/PERK around the phosphorylation site of threonine 981 (R-H-TP-G-Q).
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3
Introduction
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
Entrez Gene ID
Human9451
Mouse13666
Rat29702
UniProt ID
HumanQ9NZJ5
MouseQ9Z2B5
RatQ9Z1Z1
Alternative Names
Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3; PRKR-Like Endoplasmic Reticulum Kinase; Pancreatic EIF2-Alpha Kinase; EC 2.7.11.1; PERK; PEK; Eukaryotic Translation Initiation Factor 2-Alpha Kinase 3; HsPEK; WRS;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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