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Rabbit Anti-EIF2S1 (Phospho-Ser51) Recombinant Antibody (EG1064) (CBMAB-EN1255-LY)

The product is antibody recognizes EIF2S1 (Phospho-Ser51). The antibody EG1064 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100.
See all EIF2S1 (Phospho-Ser51) antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1064
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IHC: 1:50~1:100

Basic Information

Immunogen
The antibody was produced against synthesized phosphopeptide derived from human eIF2α around the phosphorylation site of serine 51 (E-L-SP-R-R).
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Eukaryotic Translation Initiation Factor 2 Subunit Alpha
Introduction
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Entrez Gene ID
Human1965
Mouse13665
Rat54318
UniProt ID
HumanP05198
MouseQ6ZWX6
RatP68101
Alternative Names
Eukaryotic Translation Initiation Factor 2 Subunit Alpha; Eukaryotic Translation Initiation Factor 2, Subunit 1 Alpha, 35kDa; EIF-2-Alpha; EIF-2alpha; EIF-2A; EIF2A;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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