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Mouse Anti-ENAM (AA 1043-1141) Recombinant Antibody (CBFYE-0211) (CBMAB-E0459-FY)

This product is mouse antibody that recognizes ENAM. The antibody CBFYE-0211 can be used for immunoassay techniques such as: ELISA, WB.
See all ENAM antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-0211
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant from ENAM with GST tag MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1043-1141

Target

Full Name
enamelin
Introduction
Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene encodes the largest protein in the enamel matrix of developing teeth. The protein is involved in the mineralization and structural organization of enamel. Defects in this gene result in amelogenesis imperfect type 1C.
Entrez Gene ID
10117
UniProt ID
Q9NRM1
Alternative Names
Enamelin; Amelogenesis Imperfecta 2, Hypocalcification (Autosomal Dominant); ADAI; AI1C; AIH2
Research Area
Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation.
Biological Process
Ameloblast differentiation Source: GO_Central
Amelogenesis Source: GO_Central
Biomineral tissue development Source: UniProtKB-KW
Positive regulation of enamel mineralization Source: GO_Central
Cellular Location
Extracellular matrix
Involvement in disease
Amelogenesis imperfecta 1B (AI1B):
An autosomal dominant defect of enamel formation. Clinical manifestations may be variable. Some cases present with generalized enamel hypoplasia resulting in small, smooth, yellow and widely spaced teeth (smooth hypoplastic AI). Others show horizontal rows of pits, grooves or a hypoplastic area in the enamel (local hypoplastic AI).
Amelogenesis imperfecta 1C (AI1C):
An autosomal recessive defect of dental enamel formation. Teeth show local hypoplastic and unmineralized enamel, and a yellow-brown discoloration. Enamel defects can be associated with facial and oral features including vertical dysgnathia and anterior openbite malocclusion.
PTM
Phosphorylated by FAM20C in vitro.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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