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Rat Anti-EPGN Recombinant Antibody (CBFYE-0957) (CBMAB-E1439-FY)

This product is rat antibody that recognizes EPGN. The antibody CBFYE-0957 can be used for immunoassay techniques such as: WB.
See all EPGN antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYE-0957
Antibody Isotype
IgG2
Application
WB

Basic Information

Immunogen
Mouse recombinant protein Epigen
Specificity
Mouse
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Epithelial Mitogen
Introduction
The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
71920
UniProt ID
Q924X1
Alternative Names
epigen; 2310069M11Rik
Research Area
Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Biological Process
Angiogenesis Source: HGNC-UCL
Epidermal growth factor receptor signaling pathway Source: GO_Central
Positive regulation of cell population proliferation Source: HGNC-UCL
Positive regulation of epidermal growth factor-activated receptor activity Source: HGNC-UCL
Positive regulation of epithelial cell proliferation Source: HGNC-UCL
Positive regulation of MAP kinase activity Source: HGNC-UCL
Positive regulation of mitotic nuclear division Source: HGNC-UCL
Cellular Location
Isoform 1&2: Membrane
Isoform 3&4&5&6: Secreted
Topology
Extracellular: 23-110
Helical: 111-131
Cytoplasmic: 132-154
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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