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Rabbit Anti-ERC2 Monoclonal Antibody (EPR9419) (CBMAB-1191-YC)

Provided herein is a rabbit monoclonal antibody against Human ERC2. The antibody, clone EPR9419, can be used for immunoassay techniques, such as WB.
See all ERC2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EPR9419
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Synthetic peptide within Human ERC2 aa 900 to the C-terminus (Cysteine residue).
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Elks/Rab6-Interacting/Cast Family Member 2
Introduction
ERC2 belongs to the Rab3-interacting molecule (RIM)-binding protein family, which form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release.
Entrez Gene ID
Human26059
Mouse238988
Rat259269
UniProt ID
HumanO15083
MouseQ6PH08
RatQ8K3M6
Alternative Names
CAST; CAST1; ELKSL; Spc110; SPBC110
Research Area
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Biological Process
Maintenance of presynaptic active zone structure Source: GO_Central
Neuromuscular synaptic transmission Source: GO_Central
Regulation of synaptic plasticity Source: GO_Central
Synaptic vesicle priming Source: Ensembl
Cellular Location
Cytoskeleton; Cytoplasm; Synapse; Presynaptic active zone. In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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