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Recombinant Mouse Anti-EVPL Recombinant Antibody (CRENV-1) (CBMAB-XB0437-YC)

Provided herein is a Mouse Recombinant Antibody against Envoplakin. The antibody can be used for immunoassay techniques, such as IHC, IF, IP, WB.
See all EVPL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CRENV-1
Antibody Isotype
IgG1
Application
IHC, IF, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Envoplakin
Introduction
EVPL is a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.
Entrez Gene ID
2125
UniProt ID
Q92817
Alternative Names
Envoplakin; 210 KDa Cornified Envelope Precursor Protein; 210 KDa Paraneoplastic Pemphigus Antigen; EVPK; P210;
Research Area
Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments.
Biological Process
Epidermis development Source: ProtInc
Intermediate filament cytoskeleton organization Source: GO_Central
Keratinization Source: UniProtKB-KW
Keratinocyte differentiation Source: UniProtKB
Peptide cross-linking Source: UniProtKB
Wound healing Source: GO_Central
Cellular Location
Cytoskeleton; Desmosome; Cornified envelope. Colocalized with DSP at desmosomes and along intermediate filaments.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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