Rabbit Anti-FASTKD1 Recombinant Antibody (EG1174) (CBMAB-EN1412-LY)

The product is antibody recognizes FAKD1. The antibody EG1174 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:10000.
See all FASTKD1 antibodies

Summary

Host Animal

Rabbit

Specificity

Human, Mouse

Clone

EG1174

Antibody Isotype

IgG

Application

WB: 1:500~1:1000 ELISA: 1:10000

Basic Information

Immunogen

The antibody was produced against synthesized peptide derived from internal of human FAKD1.

Specificity

Human, Mouse

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

FAST Kinase Domains 1

Introduction

FASTKD1 (FAST Kinase Domains 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein kinase activity. An important paralog of this gene is FASTKD3.

Entrez Gene ID

Human	79675
Mouse	320720

UniProt ID

Human	Q53R41
Mouse	Q6DI86

Alternative Names

FAST Kinase Domains 1; KIAA1800;

Research Area

Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.

Biological Process

Mitochondrial RNA metabolic process Source: UniProtKB
Regulation of mitochondrial mRNA stability Source: UniProtKB

Cellular Location

Mitochondrion. Preferentially localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly (PubMed:28335001).

References

Noble, A. J., Pearson, J. F., Boden, J. M., Horwood, L. J., Kennedy, M. A., & Osborne, A. J. (2021). Hypomethylation in FASTKD1 detected in the association between in utero tobacco exposure and conduct problem in a New Zealand longitudinal study. bioRxiv.

Marshall, K. D., Klutho, P. J., Song, L., Krenz, M., & Baines, C. P. (2019). The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death. American Journal of Physiology-Cell Physiology, 317(3), C584-C599.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
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Second antibody and isotype control

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