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Mouse Anti-FBXW12 (AA 265-355) Recombinant Antibody (CBXF-0424) (CBMAB-F0368-CQ)

This product is a mouse antibody that recognizes FBXW12 (AA 265-355). The antibody CBXF-0424 can be used for immunoassay techniques such as: ELISA, WB.
See all FBXW12 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0424
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 265-355

Target

Full Name
F-box and WD repeat domain containing 12
Introduction
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Entrez Gene ID
285231
UniProt ID
Q6X9E4
Alternative Names
F-Box And WD Repeat Domain Containing 12; F-Box Only Protein 35; F-Box And WD-40 Domain-Containing Protein 12; F-Box And WD-40 Domain Protein 12; FBXO35; FBXO12; FBW12; F-Box- And WD40-Repeat-Containing Protein; F-Box/WD Repeat-Containing Protein 12;
Research Area
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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