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Mouse Anti-FGF11 Recombinant Antibody (CBXF-0535) (CBMAB-F1440-CQ)

This product is a mouse antibody that recognizes FGF11. The antibody CBXF-0535 can be used for immunoassay techniques such as: WB, ICC, IHC-P, IHC-Fr, ELISA.
See all FGF11 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0535
Antibody Isotype
IgG
Application
WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen
Fibroblast Growth Factor 11
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH7.4, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fibroblast Growth Factor 11
Introduction
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
2256
UniProt ID
Q92914
Alternative Names
Fibroblast Growth Factor 11; Fibroblast Growth Factor Homologous Factor 3; FGF-11; FHF-3; FHF3;
Research Area
Probably involved in nervous system development and function.
Biological Process
Cell-cell signaling Source: ProtInc
Nervous system development Source: ProtInc
Regulation of voltage-gated sodium channel activity Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Extracellular region; Nucleus; Cytoplasm

Kang, H. R., Seong, M. S., Yim, H. S., Lee, J. H., Cha, S. H., & Cheong, J. (2022). Fibroblast growth factor 11 inhibits foot-and-mouth disease virus gene expression and replication in vitro. Journal of Veterinary Medical Science, 21-0461.

Lee, K. W., An, Y. J., Lee, J., Jung, Y. E., Ko, I. Y., Jin, J., ... & Yim, H. S. (2022). Expression and purification of intracrine human FGF 11 and study of its FGFR-dependent biological activity. Journal of Microbiology, 60(11), 1086-1094.

Cho, J. H., Kim, K., Cho, H. C., Lee, J., & Kim, E. K. (2022). Silencing of hypothalamic FGF11 prevents diet-induced obesity. Molecular Brain, 15(1), 1-16.

Wu, X., Li, M., Li, Y., Deng, Y., Ke, S., Li, F., ... & Zhou, S. (2021). Fibroblast growth factor 11 (FGF11) promotes non-small cell lung cancer (NSCLC) progression by regulating hypoxia signaling pathway. Journal of translational medicine, 19(1), 1-14.

Liu, H., Wang, X., Wang, Z. Y., & Li, L. (2020). Circ_0080425 inhibits cell proliferation and fibrosis in diabetic nephropathy via sponging miR‐24‐3p and targeting fibroblast growth factor 11. Journal of cellular physiology, 235(5), 4520-4529.

Khalafian, G., Entezari, M., & Bikhof Torbati, M. (2020). Investigating FGF11 gene transcription level in cancer cells among colorectal cancer patients. Medical Science Journal of Islamic Azad Univesity-Tehran Medical Branch, 30(1), 51-58.

Lee, K. W., Jeong, J. Y., An, Y. J., Lee, J. H., & Yim, H. S. (2019). FGF11 influences 3T3‐L1 preadipocyte differentiation by modulating the expression of PPARγ regulators. FEBS Open bio, 9(4), 769-780.

Cheng, S., Cui, Y., Fan, L., Mu, X., & Hua, Y. (2018). T2DM inhibition of endothelial miR-342-3p facilitates angiogenic dysfunction via repression of FGF11 signaling. Biochemical and biophysical research communications, 503(1), 71-78.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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