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Mouse Anti-FIGN Recombinant Antibody (2F8) (CBMAB-A2989-LY)

The product is antibody recognizes FIGN. The antibody 2F8 immunoassay techniques such as: WB, ELISA.
See all FIGN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2F8
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
FIGN (NP_060556.2, 77 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Fidgetin, Microtubule Severing Factor
Entrez Gene ID
55137
UniProt ID
Q5HY92
Function
ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Cytoplasmic microtubule organization Source: GO_Central
Cellular Location
Centrosome; Nucleus matrix. Localizes to centrosomes throughout mitosis and to the spindle midzone during telophase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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