Rabbit Anti-FOXD4 Recombinant Antibody (EG1224) (CBMAB-EN1481-LY)

The product is antibody recognizes FOXD4. The antibody EG1224 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:10000.
See all FOXD4 antibodies

Datasheet

Summary

Host Animal

Rabbit

Specificity

Human, Mouse

Clone

EG1224

Antibody Isotype

IgG

Application

WB: 1:500~1:1000 ELISA: 1:10000

Basic Information

Immunogen

The antibody was produced against synthesized peptide derived from Internal of human FOXD4.

Specificity

Human, Mouse

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

forkhead box D4

Introduction

This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality.

Entrez Gene ID

Human	2298
Mouse	14237

UniProt ID

Human	Q12950
Mouse	Q60688

Alternative Names

FKHL9; FOXD4A; FREAC5; FREAC-5

Biological Process

Anatomical structure morphogenesis Source: GO_Central
Cell differentiation Source: GO_Central
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

References

McMahon, R., Sibbritt, T., Aryamanesh, N., Masamsetti, V. P., & Tam, P. P. (2022). Loss of Foxd4 Impacts Neurulation and Cranial Neural Crest Specification During Early Head Development. Frontiers in Cell and Developmental Biology, 9, 3957.

Wang, L. J., Wang, W. L., Gao, H., Bai, Y. Z., & Zhang, S. C. (2018). FOXD3/FOXD4 is required for the development of hindgut in the rat model of anorectal malformation. Experimental Biology and Medicine, 243(4), 327-333.

Chen, C., Aihemaiti, M., Zhang, X., Qu, H., Jiao, J., Sun, Q., & Yu, W. (2018). FOXD4 induces tumor progression in colorectal cancer by regulation of the SNAI3/CDH1 axis. Cancer biology & therapy, 19(11), 1065-1071.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
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Second antibody and isotype control

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