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Mouse Anti-GNRHR2 Recombinant Antibody (CBLG1-164) (CBMAB-G0594-LY)

This product is antibody recognizes GNRHR2. The antibody CBLG1-164 immunoassay techniques such as: ELISA, WB.
See all GNRHR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-164
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.09% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
gonadotropin-releasing hormone (type 2) receptor 2
Introduction
In non-hominoid primates and non-mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven-transmembrane G-protein coupled receptor. However, in human, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that the human GnRHR2 transcription occurs but the gene does not likely produce a functional multi-transmembrane protein. A non-transcribed pseudogene of GnRHR2 is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2013]
Entrez Gene ID
114814
UniProt ID
Q96P88
Alternative Names
Gonadotropin Releasing Hormone Receptor 2 (Pseudogene); Type II GnRH Receptor; GnRH-II-R; Gonadotropin-Releasing Hormone (Type 2) Receptor 2; Pseudogene; Gonadotropin-Releasing Hormone (Type 2) Receptor 2; GnRH Receptor II 5TM; GnRH II Receptor;
Function
Putative receptor for gonadotropin releasing hormone II (GnRH II) which is most probably non-functional.
Biological Process
G protein-coupled receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-28
Helical: 29-49
Cytoplasmic: 50-67
Helical: 68-88
Extracellular: 89-115
Helical: 116-136
Cytoplasmic: 137-177
Helical: 178-198
Extracellular: 199-216
Helical: 217-237
Cytoplasmic: 238-292
PTM
Phosphorylated on the C-terminal cytoplasmic tail.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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