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Mouse Anti-GPR89A (AA 175-285) Recombinant Antibody (CBFYH-0461) (CBMAB-H1333-FY)

This product is mouse antibody that recognizes GPR89A. The antibody CBFYH-0461 can be used for immunoassay techniques such as: ELISA.
See all GPR89A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0461
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant from human GPR89 with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 175-285

Target

Full Name
G protein-coupled receptor 89A
Introduction
GPR89A is a nearly identical copy of the GPR89B gene (MIM 612806).
Entrez Gene ID
653519
UniProt ID
B7ZAQ6
Alternative Names
G Protein-Coupled Receptor 89A; Putative NF-Kappa-B-Activating Protein 90; Putative MAPK-Activating Protein PM01; GPR89; SH120; Golgi PH Regulator A; Protein GPR89A
Function
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (PubMed:12761501, PubMed:18794847).

Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity).
Biological Process
Intracellular pH reduction Source: UniProtKB
Positive regulation of I-kappaB kinase/NF-kappaB signaling Source: UniProtKB
Protein transport Source: UniProtKB-KW
Regulation of ion transmembrane transport Source: UniProtKB-KW
T cell differentiation Source: UniProtKB
Cellular Location
Golgi apparatus membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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