Mouse Anti-GUCY1A2 Recombinant Antibody (CBXS-0983) (CBMAB-S3889-CQ)

This product is a mouse antibody that recognizes GUCY1A2. The antibody CBXS-0983 can be used for immunoassay techniques such as: ELISA, WB.
See all GUCY1A2 antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBXS-0983

Antibody Isotype

IgG2a

Application

ELISA, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Preservative

0.1% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

guanylate cyclase 1 soluble subunit alpha 2

Entrez Gene ID

2977

UniProt ID

P33402

Alternative Names

GC-SA2; GUC1A2

Function

Has guanylyl cyclase on binding to the beta-1 subunit.

Isoform 2 acts as a negative regulator of guanylyl cyclase activity as it forms non-functional heterodimers with the beta subunits.

Biological Process

Intracellular signal transduction Source: InterPro
Positive regulation of nitric oxide mediated signal transduction Source: Ensembl
Signal transduction Source: ProtInc

Cellular Location

Cytoplasm

References

Wang, F., Ma, Q., Dong, X., Wang, T., & Ma, C. (2023). circ-Gucy1a2 Protects Mice from Cerebral Ischemia-Reperfusion Injury by Attenuating Neuronal Apoptosis and Mitochondrial Membrane Potential Loss. Journal of Investigative Surgery, 36(1), 2152509.

Wei, M., Huang, S., Zhu, M., & Pan, X. (2022). Prognostic Value and Biological Significance of GUCY1A2 in Gastric Cancer: A Bioinformatics Analysis Base on TCGA Database. World Journal of Cancer and Oncology Research, 19-28.

Li, X., Chen, X., Hu, X., Shen, Y., Xu, R., Wu, L., & Shen, X. (2021). Overexpression of GUCY1A2 correlates with poor prognosis in gastric cancer patients. Frontiers in Oncology, 1977.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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