Sign in or Register   Sign in or Register
  |  

Mouse Anti-ITGAD Recombinant Antibody (CA11.8H2) (CBMAB-C5159WJ)

This product is a Mouse antibody that recognizes ITGAD. This antibody CA11.8H2 can be used for immunoassay techniques such as: IHC-Fr, IP, FC.
See all ITGAD antibodies

Summary

Host Animal
Mouse
Specificity
Dog
Clone
CA11.8H2
Antibody Isotype
IgG1
Application
IHC-Fr, IP, FC

Basic Information

Specificity
Dog
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1.0 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Integrin Subunit Alpha D
Introduction
This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Entrez Gene ID
489930
UniProt ID
E2RTG5
Alternative Names
Integrin Subunit Alpha D
Function
Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood.
Biological Process
Heterotypic cell-cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Immune response1 PublicationNAS:UniProtKB
Integrin-mediated signaling pathwayIEA:UniProtKB-KW
Cellular Location
Membrane
Topology
Extracellular: 18-1099
Helical: 1100-1120
Cytoplasmic: 1121-1161
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ITGAD Recombinant Antibody (CA11.8H2)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare