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Rabbit Anti-KCNQ3 (Phospho-Thr246) Recombinant Antibody (EG1770) (CBMAB-EN2109-LY)

The product is antibody recognizes KCNQ3 (Phospho-Thr246). The antibody EG1770 immunoassay techniques such as: IHC: 1:50~1:100 ELISA: 1:20000.
See all KCNQ3 (Phospho-Thr246) antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1770
Antibody Isotype
IgG
Application
IHC: 1:50~1:100 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized phosphopeptide derived from human Kv7.3/KCNQ3 around the phosphorylation site of threonine 246 (G-G-TP-W-K).
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
potassium voltage-gated channel subfamily Q member 3
Introduction
This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants.
Entrez Gene ID
Human3786
Mouse110862
Rat29682
UniProt ID
HumanO43525
MouseQ8K3F6
RatO88944
Alternative Names
EBN2; BFNC2; KV7.3
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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