Sign in or Register   Sign in or Register
  |  

Mouse Anti-KYAT1 Recombinant Antibody (1B12) (CBMAB-A1154-LY)

The product is antibody recognizes CCBL1. The antibody 1B12 immunoassay techniques such as: WB, ELISA.
See all KYAT1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B12
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
CCBL1 (AAH33685, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Kynurenine Aminotransferase 1
Introduction
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq]
Entrez Gene ID
883
UniProt ID
Q16773
Alternative Names
FLJ95217; GTK; KAT1; KATI; MGC29624
Function
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others (PubMed:19338303, PubMed:28097769).
Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites (PubMed:7883047).
Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (PubMed:7883047).
Biological Process
Biosynthetic processIEA:InterPro
Cellular modified amino acid metabolic processIEA:InterPro
Kynurenine metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
L-kynurenine catabolic processIEA:UniProtKB-UniPathway
Cellular Location
Cytoplasm, cytosol
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KYAT1 Recombinant Antibody (1B12)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare