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Mouse Anti-M. bovis groEL Recombinant Antibody (3F7) (CBMAB-V208-0696-CQ)

This product is a mouse antibody that recognizes M. bovis groEL. The antibody 3F7 can be used for immunoassay techniques such as: WB.
See all M. bovis groEL antibodies

Summary

Host Animal
Mouse
Specificity
M. bovis
Clone
3F7
Antibody Isotype
IgM
Application
WB

Basic Information

Immunogen
GroEL / Hsp65 antibody was raised against recombinant protein isolated from M. bovis
Specificity
M. bovis
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Mycobacterium bovis groEL
Introduction
The bacterial chaperonin groEL is a double toroidal assembly, which together with the action of the ring-shaped oligomeric cochaperonin, GroES, facilitates protein folding in an ATP dependent manner.
Alternative Names
Mycobacterium bovis groEL; M. bovis groEL
Function
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Involved in copper homeostasis (PubMed:32812602).
Binds copper and may help maintaining copper homeostasis when copper is present in excess, notably in the macrophage phagosome, by acting as a metal storage protein (PubMed:32812602).
Increases copper tolerance during biofilm formation (PubMed:32812602).
In vitro binds to human CD209 (DC-SIGN) and may help mediate adherence to host cells (PubMed:21203928).
Biological Process
Protein refoldingIEA:UniProtKB-UniRule
Cellular Location
Cytoplasm
Although thought of as a cytoplasmic chaperone this protein has been found to interact in vitro with a host extracellular protein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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