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Mouse Anti-M. tuberculosis ilvC Recombinant Antibody (CBMC-C0882) (CBMAB-V208-0537-CQ)

This product is a mouse antibody that recognizes M. tuberculosis ilvC. The antibody CBMC-C0882 can be used for immunoassay techniques such as: WB, ELISA.
See all M. tuberculosis ilvC antibodies

Summary

Host Animal
Mouse
Specificity
M. tuberculosis
Clone
CBMC-C0882
Antibody Isotype
IgG1
Application
WB, ELISA

Basic Information

Immunogen
Recombinant ilvC
Specificity
M. tuberculosis
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ketol-acid reductoisomerase
Introduction
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. It is also able to use 3-hydroxypyruvate (HP).
Entrez Gene ID
UniProt ID
Alternative Names
ilvC; ketol-acid reductoisomerase; ketol-acid reductoisomerase; acetohydroxy-acid isomeroreductase (alpha-keto-beta-hydroxylacil reductoisomerase)
Function
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. It is also able to use 3-hydroxypyruvate (HP).
Biological Process
Isoleucine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Valine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytosol
Plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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