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Mouse Anti-NOB1 Recombinant Antibody (1C12) (CBMAB-N2851-WJ)

This product is a Mouse antibody that recognizes NOB1. The antibody 1C12 can be used for immunoassay techniques such as: WB.
See all NOB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C12
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NIN1/PSMD8 Binding Protein 1 Homolog
Introduction
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]
Entrez Gene ID
28987
UniProt ID
Q9ULX3
Alternative Names
NIN1/PSMD8 Binding Protein 1 Homolog; Phosphorylation Regulatory Protein HP-10; NIN1/RPN12 Binding Protein 1 Homolog; Nin One Binding Protein; PSMD8 Binding Protein 1; Protein ART-4; PSMD8BP1; NOB1P;
Function
May play a role in mRNA degradation (Probable). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity).
Biological Process
Cleavage involved in rRNA processingIEA:InterPro
Maturation of SSU-rRNAManual Assertion Based On ExperimentIBA:GO_Central
rRNA processingTAS:Reactome
Visual perceptionIEA:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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