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Mouse Anti-PDCD1 Recombinant Antibody (J105) (CBMAB-C4048-CN)

This product is a Mouse antibody that recognizes PDCD1. The antibody J105 can be used for immunoassay techniques such as: FC.
Host Species
Mouse
Application
FC
Antibody Isotype
IgG1
Cross Reactivity
Human
Clone
J105
Introduction
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Alternative Name
Programmed Cell Death 1; Systemic Lupus Erythematosus Susceptibility 2; Protein PD-1; HPD-1; PD1; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1;
Entrez Gene ID
UniProt ID

This product has been referenced in:

Lee, S. W. L., Adriani, G., Ceccarello, E., Pavesi, A., Tan, A. T., Bertoletti, A., ... & Wong, S. C. (2018). Corrigendum: Characterizing the Role of Monocytes in T Cell Cancer Immunotherapy Using a 3D Microfluidic Model. Frontiers in immunology, 9, 1719.

Garcia-Bates, T. M., Kim, E., Concha-Benavente, F., Trivedi, S., Mailliard, R. B., Gambotto, A., & Ferris, R. L. (2016). Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell–Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti–Programmed Death-1. The Journal of Immunology, 196(6), 2870-2878.

Das, R., Verma, R., Sznol, M., Boddupalli, C. S., Gettinger, S. N., Kluger, H., ... & Dhodapkar, K. M. (2015). Combination therapy with anti–CTLA-4 and anti–PD-1 leads to distinct immunologic changes in vivo. The Journal of Immunology, 194(3), 950-959.

Lee, S. W. L., Adriani, G., Ceccarello, E., Pavesi, A., Tan, A. T., Bertoletti, A., ... & Wong, S. C. (2018). Characterizing the role of monocytes in T cell cancer immunotherapy using a 3D microfluidic model. Frontiers in immunology, 9, 416.

Cherkassky, L., Morello, A., Villena-Vargas, J., Feng, Y., Dimitrov, D. S., Jones, D. R., ... & Adusumilli, P. S. (2016). Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition. The Journal of clinical investigation, 126(8), 3130-3144.

Planès, R., BenMohamed, L., Leghmari, K., Delobel, P., Izopet, J., & Bahraoui, E. (2014). HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha-and toll-like receptor 4-mediated mechanisms. Journal of virology, 88(12), 6672-6689.

Cat CBMAB-C4048-CN
Conjugates
Size
Price $
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