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Rabbit Anti-PDE7B Recombinant Antibody (EPR11491) (CBMAB-1662-CN)

This product is a rabbit antibody that recognizes PDE7B of human. The antibody EPR11491 can be used for immunoassay techniques such as: IF, FC, IHC-P, WB.
See all PDE7B antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EPR11491
Antibody Isotype
IgG
Application
IF, FC, IHC-P, WB

Basic Information

Immunogen
Synthetic peptide within Human PDE7B aa. 1-100 (Cysteine residue).
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
49% PBS, 50% Glycerol, 0.05% BSA, pH 7.2
Preservative
0.01% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Phosphodiesterase 7B
Introduction
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. The protein may be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
Entrez Gene ID
Human27115
Mouse29863
Rat140929
UniProt ID
HumanQ9NP56
MouseQ9QXQ1
RatQ8VIE4
Alternative Names
bA472E5.1
Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10814504, PubMed:10872825).
May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (PubMed:10814504).
Biological Process
cAMP catabolic processIEA:UniProtKB-UniPathway
cAMP-mediated signalingManual Assertion Based On ExperimentIDA:UniProtKB
Chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
synapse
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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