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Rat Anti-PGLYRP2 Recombinant Antibody (15H118) (CBMAB-P1586-YC)

Provided herein is a Rat monoclonal antibody against Mouse Peptidoglycan Recognition Protein 2. The antibody can be used for immunoassay techniques, such as FC, WB.
See all PGLYRP2 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
15H118
Antibody Isotype
IgG
Application
FC, WB

Basic Information

Immunogen
Recombinant protein corresponding to mouse PGRP-L
Specificity
Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized from PBS
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Peptidoglycan Recognition Protein 2
Introduction
PGLYRP2 is a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments.
Entrez Gene ID
UniProt ID
Alternative Names
Peptidoglycan Recognition Protein 2; Peptidoglycan Recognition Protein Long; N-Acetylmuramoyl-L-Alanine Amidase; PGLYRPL; PGRP-L; PGRPL; Peptidoglycan Recognition Protein L Precursor; Peptidoglycan Recognition Protein-Like;
Function
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
Biological Process
Biological process involved in interaction with hostIEA:Ensembl
Defense response to Gram-positive bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Detection of bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Innate immune response1 PublicationNAS:UniProtKB
Negative regulation of interferon-gamma productionIEA:Ensembl
Negative regulation of natural killer cell differentiation involved in immune responseIEA:Ensembl
Peptide amidation1 PublicationNAS:UniProtKB
Peptidoglycan catabolic processIEA:InterPro
Regulation of inflammatory responseIEA:Ensembl
Cellular Location
Secreted
Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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