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Recombinant Rabbit Anti-Phospho-BTK-Y223 Antibody (CBAb268) (CBMAB-Ab268-LY)

The product is antibody recognizes Phospho-BTK-Y223. The antibody immunoassay techniques such as: WB 1:500-1:2000; IP 1:20-1:50.
See all Phospho-BTK-Y223 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBAb268
Antibody Isotype
IgG
Application
WB 1:500-1:2000; IP 1:20-1:50

Basic Information

Immunogen
A phospho specific peptide corresponding to residues surrounding Y223 of human BTK
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Introduction
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
695
UniProt ID
Q06187
Alternative Names
BTK; AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA; Bruton tyrosine kinase
Function
695
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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