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Recombinant Rabbit Anti-Phospho-EIF2AK2-T446 Antibody (CBAb260) (CBMAB-Ab260-LY)

The product is antibody recognizes Phospho-EIF2AK2-T446. The antibody immunoassay techniques such as: WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200; IP 1:20-1:50.
Host Species
Rabbit
Application
WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200; IP 1:20-1:50
Immunogen
A phospho specific peptide corresponding to residues surrounding T446 of human EIF2AK2
Antibody Isotype
IgG
Specificity
Human
Cross Reactivity
Human
Clone
CBAb260
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Alternative Name
EIF2AK2; EIF2AK1; PKR; PPP1R83; PRKR; eukaryotic translation initiation factor 2 alpha kinase 2
Entrez Gene ID
UniProt ID
Cat CBMAB-Ab260-LY
Conjugates
Size
Price $
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