Sign in or Register   Sign in or Register
  |  

Mouse Anti-RFC3 Recombinant Antibody (CBCNR-426) (CBMAB-R2327-CN)

This product is a Mouse antibody that recognizes RFC3. The antibody CBCNR-426 can be used for immunoassay techniques such as: IP, ELISA, WB.
See all RFC3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-426
Antibody Isotype
IgG2a, κ
Application
IP, ELISA, WB

Basic Information

Immunogen
RFC3 (H00149, aa. 257-356) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2

Target

Full Name
replication factor C (activator 1) 3, 38kDa
Introduction
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Entrez Gene ID
5983
UniProt ID
P40938
Alternative Names
Replication Factor C Subunit 3; A1 38 KDa Subunit; Replication Factor C (Activator 1) 3, 38kDa; Replication Factor C 38 KDa Subunit; Activator 1 38 KDa Subunit; Activator 1 Subunit 3;
Function
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
Biological Process
Biological Process DNA duplex unwindingIEA:GOC
Biological Process DNA repairManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA replicationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process DNA strand elongation involved in DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process DNA synthesis involved in DNA repairManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process DNA-templated DNA replicationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of DNA-directed DNA polymerase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to organophosphorusManual Assertion Based On ExperimentIEP:UniProtKB
Cellular Location
Nucleus
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-RFC3 Recombinant Antibody (CBCNR-426)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare