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Rat Anti-SIGLECE Recombinant Antibody (CBXS-1917) (CBMAB-S0139-CQ)

This product is a rat antibody that recognizes SIGLECE. The antibody CBXS-1917 can be used for immunoassay techniques such as: FC.
See all SIGLECE antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXS-1917
Antibody Isotype
IgG2b
Application
FC

Basic Information

Immunogen
NS0-derived recombinant mouse Siglec-E, Gln19-Phe354, Accession # Q91Y57
Specificity
Mouse
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
A saline solution, BSA
Preservative
Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sialic acid binding Ig-like lectin E
Introduction
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Entrez Gene ID
83382
UniProt ID
Q91Y57
Alternative Names
Cd170; Siglec12; Siglec5; Siglec9; Siglecl1; mSiglec-E
Cellular Location
Integral component of membrane
Topology
Helical: 350-375
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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