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Mouse Anti-SLC35A3 Recombinant Antibody (CBXS-0989) (CBMAB-S3894-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0989
Antibody Isotype
IgG2a, κ
Application
S-ELISA, ELISA, WB

Basic Information

Immunogen
SLC35A3 (NP_036375, 61 a.a.-113 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
Introduction
This gene encodes a UDP-N-acetylglucosamine transporter found in the golgi apparatus membrane. In cattle, a missense mutation in this gene causes complex vertebral malformation. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
23443
UniProt ID
Q9Y2D2
Alternative Names
Solute Carrier Family 35 Member A3; Solute Carrier Family 35 (UDP-N-Acetylglucosamine (UDP-GlcNAc) Transporter), Member A3; Solute Carrier Family 35 (UDP-N-Acetylglucosamine (UDP-GlcNAc) Transporter), Member 3; Golgi UDP-GlcNAc Transporter; UDP-N-Acetylglucosamine Transporter; AMRS;
Function
Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides.
Biological Process
Biological Process carbohydrate transportIEA:UniProtKB-KW
Biological Process UDP-N-acetylglucosamine metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process UDP-N-acetylglucosamine transmembrane transportManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Golgi apparatus membrane
Involvement in disease
Arthrogryposis, impaired intellectual development, and seizures (AMRS):
A disease characterized by arthrogryposis, intellectual disability, autism spectrum disorder, and epilepsy. Additional features include limb malformations, distal joint involvement, microcephaly, retromicrognathia, and general muscle hypotonia.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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