Mouse Anti-SLC35A3 Recombinant Antibody (CBXS-4990) (CBMAB-S2212-CQ)

Name: Mouse Anti-SLC35A3 Recombinant Antibody (CBXS-4990)
SKU: CBMAB-S2212-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-4990

Application

ELISA, WB

Immunogen

SLC35A3 (NP_036375, 61 a.a.-113 a.a) partial recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3

Introduction

This gene encodes a UDP-N-acetylglucosamine transporter found in the golgi apparatus membrane. In cattle, a missense mutation in this gene causes complex vertebral malformation. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

23443

UniProt ID

Q9Y2D2

Alternative Names

Solute Carrier Family 35 Member A3; Solute Carrier Family 35 (UDP-N-Acetylglucosamine (UDP-GlcNAc) Transporter), Member A3; Solute Carrier Family 35 (UDP-N-Acetylglucosamine (UDP-GlcNAc) Transporter), Member 3; Golgi UDP-GlcNAc Transporter; UDP-N-Acetylglucosamine Transporter; AMRS;

Function

Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides.

Biological Process

Biological Process carbohydrate transportIEA:UniProtKB-KW
Biological Process UDP-N-acetylglucosamine metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process UDP-N-acetylglucosamine transmembrane transportManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Golgi apparatus membrane

Involvement in disease

Arthrogryposis, impaired intellectual development, and seizures (AMRS):
A disease characterized by arthrogryposis, intellectual disability, autism spectrum disorder, and epilepsy. Additional features include limb malformations, distal joint involvement, microcephaly, retromicrognathia, and general muscle hypotonia.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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