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Rabbit Anti-STX16 Recombinant Antibody (CBXS-1626) (CBMAB-S4475-CQ)

This product is a rabbit antibody that recognizes STX16. The antibody CBXS-1626 can be used for immunoassay techniques such as: WB, IHC-P, IF.
See all STX16 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1626
Antibody Isotype
IgG
Application
WB, IHC-P, IF

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
syntaxin 16
Introduction
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene.
Entrez Gene ID
Human8675
Mouse228960
Rat362283
UniProt ID
HumanO14662
MouseQ8BVI5
RatD3Z9R7
Alternative Names
SYN16
Function
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
Biological Process
Biological Process endocytic recyclingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Golgi apparatus membrane
Isoform C
Cytoplasm
Involvement in disease
Pseudohypoparathyroidism 1B (PHP1B):
A disorder characterized by end-organ resistance to parathyroid hormone, hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH.
Topology
Cytoplasmic: 1-301
Helical: 302-322
Vesicular: 323-325
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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