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Mouse Anti-TMEM123 Recombinant Antibody (CBYJT-3486) (CBMAB-T2811-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TMEM123 (Transmembrane Protein 123). The antibody can be used for immunoassay techniques, such as ELISA, WB.
Host Animal
Mouse
Application
ELISA, WB
Immunogen
TMEM123 (NP_443164, 34 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: ETLQHVPSDH TNETSNSTVK PPTSVASDSS NTTVTTMKPT AASNTTTPGM VSTNMTSTTL KSTPKTTSVS QNTSQISTST MTVTHNSSVT SAASSVTITT
Antibody Isotype
IgG1, κ
Specificity
Human
Cross Reactivity
Human
Clone
CBYJT-3486
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to play a role as a cell surface receptor that mediates cell death.
Alternative Name
Transmembrane Protein 123; Pro-Oncosis Receptor Inducing Membrane Injury; KCT-3; KCT3; Pro Oncosis Receptor Inducing Membrane Injury Gene; Keratinocytes Associated Transmembrane Protein 3
Entrez Gene ID
UniProt ID
Cat CBMAB-T2811-YJ
Conjugates
Size
Price $
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