Sign in or Register   Sign in or Register
  |  

Mouse Anti-TMEM123 Recombinant Antibody (CBYJT-3486) (CBMAB-T2811-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TMEM123 (Transmembrane Protein 123). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TMEM123 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3486
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
TMEM123 (NP_443164, 34 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: ETLQHVPSDH TNETSNSTVK PPTSVASDSS NTTVTTMKPT AASNTTTPGM VSTNMTSTTL KSTPKTTSVS QNTSQISTST MTVTHNSSVT SAASSVTITT
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 34-133

Target

Full Name
transmembrane protein 123
Introduction
TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to play a role as a cell surface receptor that mediates cell death.
Entrez Gene ID
114908
UniProt ID
Q8N131
Alternative Names
Transmembrane Protein 123; Pro-Oncosis Receptor Inducing Membrane Injury; KCT-3; KCT3; Pro Oncosis Receptor Inducing Membrane Injury Gene; Keratinocytes Associated Transmembrane Protein 3
Function
Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.
Biological Process
Oncosis
Cellular Location
Membrane
Topology
Extracellular: 27-166
Helical: 167-187
Cytoplasmic: 188-208
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TMEM123 Recombinant Antibody (CBYJT-3486)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare