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Mouse Anti-VC1457 Recombinant Antibody (CBMY-C0274) (CBMAB-V208-C0277-YY)

This product is mouse antibody that recognizes V. cholerae VC1457. The antibody CBMY-C0274 can be used for immunoassay techniques such as: ELISA
See all V. cholerae VC1457 antibodies

Summary

Host Animal
Mouse
Specificity
V. cholerae
Clone
CBMY-C0274
Application
ELISA

Basic Information

Immunogen
The immunogen for anti-VC1457 antibody: vibrio cholerae extract
Specificity
V. cholerae
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vibrio cholerae Cholera enterotoxin subunit A
Introduction
The A1 chain catalyzes the ADP-ribosylation of Gs alpha, a GTP-binding regulatory protein, to activate the adenylate cyclase. This leads to an overproduction of cAMP and eventually to a hypersecretion of chloride and bicarbonate followed by water, resulting in the characteristic cholera stool. The A2 chain tethers A1 to the pentameric ring.
Function
The A1 chain catalyzes the ADP-ribosylation of Gs alpha, a GTP-binding regulatory protein, to activate the adenylate cyclase. This leads to an overproduction of cAMP and eventually to a hypersecretion of chloride and bicarbonate followed by water, resulting in the characteristic cholera stool. The A2 chain tethers A1 to the pentameric ring.
Biological Process
Biological Process localization Source:DisProt1 Publication
Biological Process positive regulation of tyrosine phosphorylation of STAT protein Source:CACAO1 Publication
Cellular Location
catalytic complex
extracellular space
periplasmic space
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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