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Mouse Anti-VIPR1 Recombinant Antibody (AS58) (CBMAB-P3781-YC)

Provided herein is a Mouse monoclonal antibody against Human Vasoactive Intestinal Peptide Receptor 1. The antibody can be used for immunoassay techniques, such as FC, WB.
See all VIPR1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
AS58
Antibody Isotype
IgG2a
Application
FC, WB

Basic Information

Immunogen
Recombinant VIPR1 receptor protein and mouse myeloma cells
Specificity
Human, Rat
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vasoactive Intestinal Peptide Receptor 1
Introduction
VIPR1 is a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase.
Entrez Gene ID
Human7433
Rat24875
UniProt ID
HumanP32241
RatP30083
Alternative Names
Vasoactive Intestinal Peptide Receptor 1; VIP And PACAP Receptor 1; PACAP Type II Receptor; PACAP-R-2; PACAP-R2; VIP-R-1; VPAC1; Pituitary Adenylate Cyclase Activating Polypeptide Receptor, Type II; Pituitary Adenylate Cyclase-Activating Polypeptide Type II Receptor; Type 1 Vasoactive Intestinal Peptide Receptor; Vasoactive Intestinal Polypeptide Receptor 1; VIP Receptor, Type I;
Function
This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27> PACAP-38.
Biological Process
Biological Process adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source:GO_Central1 Publication
Biological Process cell surface receptor signaling pathway Source:InterPro
Biological Process G protein-coupled receptor signaling pathway Source:ProtInc1 Publication
Biological Process G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source:GO_Central1 Publication
Biological Process positive regulation of cell population proliferation Source:ProtInc1 Publication
Cellular Location
Cell membrane
Topology
Extracellular: 31-142
Helical: 143-167
Cytoplasmic: 168-174
Helical: 175-194
Extracellular: 195-216
Helical: 217-240
Cytoplasmic: 241-254
Helical: 255-276
Extracellular: 277-292
Helical: 293-316
Cytoplasmic: 317-341
Helical: 342-361
Extracellular: 362-373
Helical: 374-393
Cytoplasmic: 394-457
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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