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EIF5A2 Matched Antibody Pair (372) (APMAB-372LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-EIF5A2 polyclonal antibody, 100 ug
Detection Antibody
Anti-EIF5A2 Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
EIF5A2 (Eukaryotic Translation Initiation Factor 5A2) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Gamma carboxylation, hypusine formation and arylsulfatase activation. Gene Ontology (GO) annotations related to this gene include RNA binding and translation elongation factor activity. An important paralog of this gene is EIF5A.
Alternative Names
Eukaryotic Translation Initiation Factor 5A2; EIF-5A-2; EIF-5A2; Eukaryotic Translation Initiation Factor 5A-2; Eukaryotic Initiation Factor 5A Isoform 2; Eukaryotic Initiation Factor 5A; EIF5AII;
Entrez Gene ID
UniProt ID
More Infomation

Zhang, Z., He, G., Lv, Y., Liu, Y., Niu, Z., Feng, Q., ... & Xu, J. (2022). HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer. Cell death & disease, 13(1), 1-12.

Zhao, G., Zhang, W., Dong, P., Watari, H., Guo, Y., Pfeffer, L. M., ... & Yue, J. (2021). EIF5A2 controls ovarian tumor growth and metastasis by promoting epithelial to mesenchymal transition via the TGFβ pathway. Cell & bioscience, 11(1), 1-12.

Zheng, Y., Li, P., Huang, H., Ye, X., Chen, W., Xu, G., & Zhang, F. (2021). Androgen receptor regulates eIF5A2 expression and promotes prostate cancer metastasis via EMT. Cell death discovery, 7(1), 1-8.

Luan, W., Ding, Y., Yuan, H., Ma, S., Ruan, H., Wang, J., ... & Bu, X. (2020). Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis. Journal of Experimental & Clinical Cancer Research, 39(1), 1-16.

Lin, Y. M., Chen, M. L., Chen, C. L., Yeh, C. M., & Sung, W. W. (2020). Overexpression of EIF5A2 predicts poor prognosis in patients with oral squamous cell carcinoma. Diagnostics, 10(7), 436.

Liu, Y., Lei, P., Qiao, H., Sun, K., Lu, X., Bao, F., ... & Xue, F. (2019). miR-9 enhances the chemosensitivity of AML cells to daunorubicin by targeting the EIF5A2/MCL-1 axis. International journal of biological sciences, 15(3), 579.

Guan, X., Gu, S., Yuan, M., Zheng, X., & Wu, J. (2019). MicroRNA‑33a‑5p overexpression sensitizes triple‑negative breast cancer to doxorubicin by inhibiting eIF5A2 and epithelial‑mesenchymal transition. Oncology Letters, 18(6), 5986-5994.

Zheng, X., Gao, L., Wang, B. T., Shen, P., Yuan, X. F., Zhang, L. Q., ... & Wang, X. M. (2019). Overexpression of EIF5A2 is associated with poor survival and aggressive tumor biology in gallbladder cancer. Histology and Histopathology, 35(6), 579-587.

Yang, Y., Cui, H., & Wang, X. (2019). Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells. Bioscience, Biotechnology, and Biochemistry, 83(3), 400-408.

Sun, J., Xu, Z., Lv, H., Wang, Y., Wang, L., Ni, Y., ... & Cheng, X. (2018). eIF5A2 regulates the resistance of gastric cancer cells to cisplatin via induction of EMT. American journal of translational research, 10(12), 4269.

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For research use only. Not intended for any clinical use.

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