CA5B
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes carbonic anhydrase 5B. CA5B, and the related CA5A gene, has its expression localized in the mitochondria though CA5B has a wider tissue distribution than CA5A, which is restricted to the liver, kidneys, and skeletal muscle. A carbonic anhydrase pseudogene (CA5BP1) is adjacent to the CA5B gene and these two loci produce CA5BP1-CA5B readthrough transcripts.
Full Name
carbonic anhydrase 5B
Function
Reversible hydration of carbon dioxide.
Biological Process
Bicarbonate transport Source: Reactome
One-carbon metabolic process Source: GO_Central
Response to bacterium Source: Ensembl
One-carbon metabolic process Source: GO_Central
Response to bacterium Source: Ensembl
Cellular Location
Mitochondrion
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Anti-CA5B antibodies
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Target: CA5B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-0033
Application*: WB
Target: CA5B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Dog
Clone: CBXC-0032
Application*: E, WB, IF, IP
Target: CA5B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Dog
Clone: CBYY-C0850
Application*: E, WB, IF, IP
Target: CA5B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-0699
Application*: E
Target: CA5B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E12
Application*: E
Target: CA5B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 008
Application*: P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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