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CCDC93

CCDC93 (Coiled-Coil Domain Containing 93) is a Protein Coding gene.
Full Name
Coiled-Coil Domain Containing 93
Function
Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (PubMed:28892079, PubMed:25355947).
Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (PubMed:25355947).
(Microbial infection) The CCC complex, in collaboration with the heterotrimeric retriever complex, mediates the exit of human papillomavirus to the cell surface.
Biological Process
Endocytic recycling Source: UniProtKB
Golgi to plasma membrane transport Source: UniProtKB
Protein transport Source: UniProtKB-KW
Cellular Location
Early endosome

Anti-CCDC93 antibodies

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Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6E11
Application*: P, WB
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A10
Application*: WB
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: CBXC-2212
Application*: WB
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: CBXC-2124
Application*: WB
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C3206
Application*: P, WB
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C3103
Application*: WB, IH
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0913
Application*: WB
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLC133-LY
Application*: WB, IP, IF, E
Target: CCDC93
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Human, Monkey
Clone: OTI6E11
Application*: IH, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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