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CD151

CD151 (CD151 Molecule (Raph Blood Group)) is a Protein Coding gene. Diseases associated with CD151 include Nephropathy With Pretibial Epidermolysis Bullosa And Deafness and Raph Blood Group System. Among its related pathways are Primary Focal Segmental Glomerulosclerosis FSGS and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include integrin binding. An important paralog of this gene is TSPAN11.
Full Name
CD151 Molecule (Raph Blood Group)
Function
Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.
(Microbial infection) Plays a role in human papillomavirus 16/HPV-16 endocytosis upon binding to cell surface receptor.
Biological Process
Cell adhesion Source: ProtInc
Cell migration Source: GO_Central
Collagen fibril organization Source: Reactome
Hemidesmosome assembly Source: Reactome
Positive regulation of cell migration Source: MGI
Positive regulation of endocytosis Source: MGI
T cell proliferation Source: Ensembl
Viral process Source: UniProtKB-KW
Wound healing, spreading of cells Source: MGI
Cellular Location
Membrane
Involvement in disease
Nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD): A disorder characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor.
Topology
Cytoplasmic: 1-18
Helical: 19-39
Extracellular: 40-57
Helical: 58-78
Cytoplasmic: 79-91
Helical: 92-112
Extracellular: 113-221
Helical: 222-242
Cytoplasmic: 243-253
PTM
Palmitoylated. Palmitoylation by ZDHHC2 regulates CD151 expression, association with other tetraspanin family proteins and function in cell adhesion.

Anti-CD151 antibodies

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Target: CD151
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 455807
Application*: F, IC, MC
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0176
Application*: E, F, IH, IP, WB
Target: CD151
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: SFA1.2B4
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0175
Application*: F
Target: CD151
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0780
Application*: F
Target: CD151
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-1199
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1010
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-3009
Application*: F, MC
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2371
Application*: WB, F, E, P, C
Target: CD151
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1110
Application*: E, WB
Target: CD151
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-0438
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0290
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP378
Application*: IF, IHC, IP, WB
Target: CD151
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CF067
Application*: ELISA, WB, IHC
Target: CD151
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLC279-LY
Application*: WB, P, F
Target: CD151
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: RLM30
Application*: WB, IHC
Target: CD151
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: SFA.2B4
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0160-6F40
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L160
Application*: FC
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1188
Application*: E, F, IH, IP, WB
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1187
Application*: WB, P, IF, IP
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1880
Application*: E, F, IH, IP, WB
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3G1
Application*: WB, P, IF/IC, IP
Target: CD151
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B2
Application*: E, WB
Target: CD151
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 210127
Application*: F, MC
Target: CD151
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 14A2.H1
Application*: F
Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11G5a
Application*: E, F, C, P, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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