CD151

CD151 (CD151 Molecule (Raph Blood Group)) is a Protein Coding gene. Diseases associated with CD151 include Nephropathy With Pretibial Epidermolysis Bullosa And Deafness and Raph Blood Group System. Among its related pathways are Primary Focal Segmental Glomerulosclerosis FSGS and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include integrin binding. An important paralog of this gene is TSPAN11.
Full Name
CD151 Molecule (Raph Blood Group)
Alternative Names
CD151 Molecule (Raph Blood Group); CD151 Antigen; Platelet-Endothelial Tetraspan Antigen 3; CD151 Antigen (Raph Blood Group); Membrane Glycoprotein SFA-1; Tetraspanin-24; Tspan-24; TSPAN24; PETA-3;
Function
Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.
(Microbial infection) Plays a role in human papillomavirus 16/HPV-16 endocytosis upon binding to cell surface receptor.
Biological Process
Cell adhesion Source: ProtInc
Cell migration Source: GO_Central
Collagen fibril organization Source: Reactome
Hemidesmosome assembly Source: Reactome
Positive regulation of cell migration Source: MGI
Positive regulation of endocytosis Source: MGI
T cell proliferation Source: Ensembl
Viral process Source: UniProtKB-KW
Wound healing, spreading of cells Source: MGI
Cellular Location
Membrane
Involvement in disease
Nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD): A disorder characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor.
Topology
Cytoplasmic: 1-18
Helical: 19-39
Extracellular: 40-57
Helical: 58-78
Cytoplasmic: 79-91
Helical: 92-112
Extracellular: 113-221
Helical: 222-242
Cytoplasmic: 243-253
PTM
Palmitoylated. Palmitoylation by ZDHHC2 regulates CD151 expression, association with other tetraspanin family proteins and function in cell adhesion.
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Anti-CD151 antibodies

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Mouse Anti-CD151 Recombinant Antibody (AG05) (V2LY-0524-LY10)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AG05
Application*: B, MC, F, IC, In Vivo, WB
In Vivo Assay Functional Assay
Datasheet SDS

Mouse Anti-CD151 Recombinant Antibody (CBT2077) (V2LY-0625-LY1642)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT2077
Application*: IH, F
Datasheet SDS

Rabbit Anti-CD151 Recombinant Antibody (CBLC279-LY) (CBMAB-C10002-LY)

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Target: CD151
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLC279-LY
Application*: WB, IH
Datasheet SDS

Human Anti-CD151 Recombinant Antibody (CBXC-0780) (CBMAB-C1894-CQ)

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Target: CD151
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0780
Application*: F, E
Datasheet SDS

Mouse Anti-CD151 Recombinant Antibody (CBFYC-1110) (CBMAB-C1168-FY)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-1110
Application*: F
Datasheet SDS

Mouse Anti-CD151 Recombinant Antibody (CBFYC-0438) (CBMAB-C0484-FY)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0438
Application*: F, IC, WB
Datasheet SDS

Mouse Anti-CD151 Recombinant Antibody (CBFYC-0290) (CBMAB-C0321-FY)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0290
Application*: E, IF, P, IP, WB
Datasheet SDS

Rat Anti-CD151 Recombinant Antibody (455807) (CBMAB-C1320-LY)

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Target: CD151
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 455807
Application*: F, IC
Datasheet SDS

Mouse Anti-CD151 Recombinant Antibody (1B2) (CBMAB-C3629-LY)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 1B2
Application*: E, WB
Datasheet SDS

Mouse Anti-CD151 Recombinant Antibody (210127) (CBMAB-C0595-LY)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 210127
Application*: F
Datasheet SDS

Mouse Anti-CD151 Recombinant Antibody (11G5a) (CBMAB-C0233-LY)

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Target: CD151
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11G5a
Application*: E, F, IF, P, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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