CLEC11A
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
Full Name
C-Type Lectin Domain Containing 11A
Function
Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts (PubMed:27976999).
Important for repair and maintenance of adult bone (By similarity).
Important for repair and maintenance of adult bone (By similarity).
Biological Process
Ossification Source: GO_Central
Positive regulation of cell population proliferation Source: UniProtKB
Positive regulation of cell population proliferation Source: UniProtKB
Cellular Location
Secreted; Cytoplasm
PTM
O-glycosylated. Probably sulfated on the O-glycans.
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Anti-CLEC11A antibodies
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CompareTarget: CLEC11A
Sensitivity: 0.048 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: CLEC11A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CF103
Application*: IH
Target: CLEC11A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1720
Application*: IF, WB, IH
Target: CLEC11A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5212
Application*: IH, WB
Target: CLEC11A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C3145
Application*: IH, WB, E
Target: CLEC11A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C3048
Application*: IF, WB, IH
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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