CSH2
CSH2 (Chorionic Somatomammotropin Hormone 2) is a Protein Coding gene. Diseases associated with CSH2 include Choriocarcinoma and Testicular Trophoblastic Tumor. Among its related pathways are Jak-STAT signaling pathway (KEGG) and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include hormone activity. An important paralog of this gene is CSH1.
Full Name
Chorionic Somatomammotropin Hormone 2
Function
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
Biological Process
Animal organ development Source: GO_Central
Growth hormone receptor signaling pathway Source: GO_Central
Positive regulation of growth Source: GO_Central
Positive regulation of receptor signaling pathway via JAK-STAT Source: GO_Central
Positive regulation of tyrosine phosphorylation of STAT protein Source: GO_Central
Response to nutrient levels Source: GO_Central
Growth hormone receptor signaling pathway Source: GO_Central
Positive regulation of growth Source: GO_Central
Positive regulation of receptor signaling pathway via JAK-STAT Source: GO_Central
Positive regulation of tyrosine phosphorylation of STAT protein Source: GO_Central
Response to nutrient levels Source: GO_Central
Cellular Location
Secreted
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Anti-CSH2 antibodies
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Target: CSH2
Sensitivity: 0.052 μg/mL
Detection Range: 0.1-40 μg/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: CSH2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-2291
Application*: WB, IP, IF, E
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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